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ONCOSTATIN M
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DeCS
Descriptor
English
:
Oncostatin M
Descriptor
Spanish
:
oncostatina M
Descriptor
Portuguese
:
Oncostatina M
Tree Number:
D12.644.276.374.562
D12.776.467.374.562
D23.529.374.562
Definition
English
:
A cytokine with both pro- and anti-inflammatory actions that depend upon the
cellular microenvironment
.
Oncostatin M
is a 28 kDa monomeric glycoprotein that is
similar
in structure to
LEUKEMIA INHIBITORY FACTOR
. Its name derives from the the
observation
that it inhibited the
growth
of tumor cells and augmented the
growth
of normal
fibroblasts.
Pharmacological Action:
Antineoplastic Agents
Growth Inhibitors
History Note
English
:
2007(1987)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52283
Unique Identifier:
D053683
Occurrence in VHL
:
Similar:
DeCS